The success of this process can vary wildly depending on the circumstances of the work and the employee's skill, as each Abnormality has its unique set of traits that determine how it will behave and what dangers it poses. Next, the management phase consists of sending these employees to extract energy from Abnormalities. In the preparation phase, the player can hire new employees, boost existing employees' stats (Fortitude, Prudence, Temperance, and Justice), assign them to different departments, and equip them with E.G.O weapons and suits, some of which are basic while others have special quirks.

The game is divided into two different phases: preparation and management (the latter of which is the 'meat' of the game). Other inspirations include television series Warehouse 13 and horror-comedy film The Cabin in the Woods. The premise is inspired by the SCP Foundation, a collaborative web fiction project about a secret organization that contains supernatural 'anomalies' in research facilities. They are tasked with overseeing the process and must command their employees to 'work' on these Abnormalities in order to fill the daily 'quota' of energy, but must also suppress them in order to place them back in their containment if they breach. The Player, who is referred as 'X', is the manager of a renewable underground power company called 'Lobotomy Corporation' that harvests energy from strange beings and objects known as 'Abnormalities'.

The third installment, dungeon role-playing game Limbus Company has been released in February 2023. The sequel, deck-building game Library of Ruina, was released for Windows and Xbox One in August 2021. Lobotomy Corporation is an indie horror strategy management simulation video game for Microsoft Windows developed and published by South Korean studio Project Moon in April 2018.

Lobotomy corporation xbox download